Heart disease and stroke are on the decline globally—but not everywhere. In fact, in regions like East and West Sub-Saharan Africa, East and Central Asia, and Oceania, cases of ischemic heart disease are on the rise. What’s behind these worrying trends? Researchers from Fudan University, writing in PLOS Global Public Health, reveal that lifestyle shifts and socioeconomic factors are major culprits.
The Global Picture: What’s Changing?
Cardiovascular diseases like ischemic heart disease (often linked to heart attacks) and stroke remain leading causes of death worldwide, responsible for 16% and 11% of global deaths in 2019, respectively. Over the last 30 years, the overall numbers have improved:
- Heart disease cases dropped from 316 to 262 per 100,000 people.
- Stroke cases fell from 181 to 151 per 100,000 people.
However, these improvements are far from evenly spread. In several rapidly developing regions, the numbers are climbing—and researchers have identified eight key factors driving these increases.
8 Lifestyle and Environmental Risks Behind the Rise
- Unhealthy diets – Diets high in trans fats or low in essential nutrients like calcium are contributing to cardiovascular issues.
- High BMI (Body Mass Index) – Rising obesity rates in many areas are linked to heart disease and stroke.
- Household air pollution – Solid fuels like wood or coal used for cooking and heating expose families to harmful air pollutants.
- Lack of exclusive breastfeeding – Inadequate breastfeeding practices can lead to health risks later in life.
- Workplace conditions – Poor ergonomic setups and exposure to harmful particles and fumes at work are significant concerns.
- Vitamin A deficiency – A lack of this critical nutrient can have long-term health effects.
- Exposure to pollutants – Occupational exposure to particulate matter, gases, and fumes is a growing issue.
- Socioeconomic transitions – Rapid lifestyle changes tied to economic development may disrupt traditional habits and introduce unhealthy ones.
The Role of Economic and Lifestyle Shifts
In many regions experiencing economic growth, people are transitioning to more urbanized and industrialized lifestyles. These changes often lead to:
- Increased consumption of processed foods.
- Reduced physical activity.
- Greater exposure to pollution.
The research suggests that these shifts are not only altering lifestyles but also creating environments where heart disease and stroke thrive.
What Can Be Done?
The findings underline the need for targeted interventions. Governments and health organizations can focus on improving access to:
- Healthy food options to combat poor diets.
- Cleaner household energy to reduce air pollution.
- Workplace safety regulations to minimize exposure to harmful substances.
For individuals, making small but impactful changes—like incorporating more fresh produce into meals, staying active, and reducing exposure to pollutants—can help reduce the risk of heart disease and stroke.
A Takeaway for the Future
The rise in ischemic heart disease and stroke in certain regions serves as a stark reminder: progress in global health is uneven. While wealthier nations benefit from healthcare advancements and healthier lifestyles, rapidly developing countries face unique challenges tied to their economic growth.
Understanding these trends helps experts develop better policies and solutions, ensuring that progress is shared across the globe. As the researchers put it, “This study reveals the pivotal role of socioeconomic development in shaping the risks of cardiovascular diseases.”

